Technology Innovations

Posts Tagged ‘Diabetes

Bangalore-based PathShodh Healthcare, a startup at the Entrepreneurship Centre of the Indian Institute of Science, has developed a hand-held device to measure eight vital parameters for diabetes, kidney failure, chronic anaemia, and malnutrition.

The device, called anuPath, has been developed by Dr. Vinay Kumar along with Professor Navakanta Bhat of Indian Institute of Science and a friend, Gautam Sharma.

According to a recent International Diabetes Federation (IDF) report, diabetes currently affects over 425 million people worldwide, and the figure is expected to reach 629 million by 2045. With 73 million diabetics, India ranks second in the world after China.

People with diabetes have an increased risk of developing a number of serious health problems. Consistently high blood glucose levels can lead to serious diseases affecting the heart and blood vessels, eyes, kidneys, nerves and teeth. In addition, people with diabetes also have a higher risk of developing infections, says the IDF report.

Currently, anuPath can test for hemoglobin, HbA1C, glycated albumin, blood glucose, serum albumin, microalbuminuria, urine ACR, and urine creatinine. It will be extendable to other markers (glycated albumin, serum creatinine, serum bilirubin, etc.) in the future. It works on a non-enzymatic- and non-antibody-based electrochemical biosensing technology. The measurement is done on electrochemical disposable test strips that contain a membrane infused with patented sensing substances. For each biomarker there is a separate disposable strip. When the user places the required sample on the electrochemical disposable test strip, anuPath detects the electrochemical outcomes and the deciphered results are displayed on the digital monitor within a minute. This enables the patient to get a comprehensive report of the status of the disease, which is essential in disease management. Read full research paper.

Presently, it can store one lakh patient reports, making it easier to share with doctors. With one international patent and eight in process, anuPath costs Rs. 50,000. The team is working on a cost effective model of about Rs. 5,000 – Rs. 10,000 for individual users to use it at home. Read more

India has about 60 million diabetics and for this group, life is an unending struggle, fraught with frequent complications such as cardiovascular diseases and renal failures. Therefore, monitoring the disease becomes an exhausting, daily ritual.

Now, a Mumbai-based company called BioSense has devised an application that can be downloaded to your smartphone. A simple cuboid plastic box houses the phone with the camera facing downwards. A strip, after being placed in a urine stream and then affixed to a holder, is then placed on top of the box.

Once Biosense’s app is launched, the camera takes repeated photographs of the strip as it changes colour, and feeds it to the app. Almost instantaneously, a thorough report tabulating 10 vital biochemicals in your body – from glucose to bilirubinW is generated. The total cost: about Rs. 2,000 versus endless sorties to the lab. The same test also keeps tabs on pregnancy issues and urinary tract infections. Read more to get a glimpse of a few other Indian innovations in health care.

Now diabetics can heave a sigh of relief. Indian scientist and IIT-Delhi alumnus Anurag Kumar, along with his team, has developed a new type of biosensor that can use a drop of tear, saliva or urine as the medium for a glucose test. Kumar is currently pursuing PhD from Purdue University in the US. The new type of biosensor can detect minute concentrations of glucose in saliva, tears and urine and is likely to incur low manufacturing cost as it can be produced with minimal processing steps.

“Its an inherently non-invasive way to estimate glucose content in the body. Since it can detect glucose in saliva and tears, it’s a platform that might eventually help to eliminate or reduce the frequency of using pinpricks for diabetes testing. We are proving its functionality,” the team said. Kumar, who hails from Talaiya, a small town in Jharkhand, is working towards commercializing the technology. Click here to read the technology details in the article written by Kounteya Sinha of Times News Network.

Suman Kapur, professor of biological sciences at Birla Institute of Technology and Science (BITS), Pilani, has developed a new cell-phone-sized blood sugar testing machine  that could cost just Rs 2, take about 10 seconds and require 1,000 times less blood than the existing glucose meters.

The new blood sugar testing machine will undergo final evaluation by July 15 and is expected to be ready for mass production by December. Instead of strips, the device uses a capillary (narrow pipe) worth Rs 2 through which the blood is transmitted to the reading device.  Kapur has used nano particles to intensify the colour code response using the ‘Colour to Frequency Censor’ technology.

The innovation could have a large social impact in India, the diabetes capital of the world. This is an excerpt from Kounteya Sinha’s news report featuring the Indian innovation. Read full article

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